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A network thermodynamic two-port element to represent the coupled flow of salt and current. Improved alternative for the equivalent circuit.

机译:网络热力学两端口元件,用于表示盐和电流的耦合流动。等效电路的改进替代方案。

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摘要

A two-port for coupled salt and current flow is created by using the network thermodynamic approach in the same manner as that for coupled solute and volume flow (Mikulecky et al., 1977b; Mikulecky, 1977). This electrochemical two-port has distinct advantages over the equivalent circuit representation and overcomes difficulties pointed out by Finkelstein and Mauro (1963). The electrochemical two-port is used to produce a schematic diagram of the coupled flows through a tissue. The network is superimposable on the tissue morphology and preserves the physical qualities of the flows and forces in each part of an organized structure (e.g., an epithelium). The topological properties are manipulated independently from the constitutive (flow-force) relations. The constitutive relations are chosen from a number of alternatives depending on the detail and rigor desired. With the topology and constitutive parameters specified, the steady-state behavior is simulated with a network simulation program. By using capacitance to represent the filling and depletion of compartments, as well as the traditional electrical capacitances, time-dependent behavior is also simulated. Nonlinear effects arising from the integration of equations describing local behavior (e.g., the Nernst-Planck equations) are dealt with explicitly. The network thermodynamic approach provides a simple, straightforward method for representing a system diagrammatically and then simulating the system's behavior from the diagram with a minimum of mathematical manipulation.
机译:通过使用网络热力学方法,以与耦合溶质和体积流相同的方式,建立了盐和电流耦合的两个端口(Mikulecky等,1977b; Mikulecky,1977)。这种电化学双端口具有优于等效电路表示的独特优势,并克服了Finkelstein和Mauro(1963)指出的困难。电化学两端口用于产生通过组织的耦合流的示意图。该网络在组织形态上是可叠加的,并在组织结构的每个部分(例如上皮)中保留了流动和力的物理性质。拓扑属性是独立于本构(流动-力)关系进行操纵的。本构关系取决于细节和所需的严格性,从许多替代方案中选择。在指定拓扑和本构参数的情况下,使用网络仿真程序对稳态行为进行仿真。通过使用电容来表示隔室的填充和耗尽以及传统的电容,还可以模拟随时间变化的行为。明确处理了由描述局部行为的方程(例如Nernst-Planck方程)的积分引起的非线性效应。网络热力学方法提供了一种简单,直接的方法,用于以图形方式表示系统,然后通过最少的数学操作即可从图中模拟系统的行为。

著录项

  • 作者

    Mikulecky, D C;

  • 作者单位
  • 年度 1979
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  • 原文格式 PDF
  • 正文语种 en
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